Job Description

Division:  Neuroscience (80001005)  

Department:  Neuroscience (90002091)  

Employment Duration: Full-time  

Summary

The Jan and Dan Duncan Neurological Research Institute (NRI) is seeking a Core Director to lead the Advanced Cellular Electrophysiology & Patch-seq Core. This facility serves as a critical hub for investigators by providing advanced cellular physiology expertise, state-of-the-art equipment, and specialized services to study the electrical and molecular properties of cells in controlled laboratory settings. The Core Director will oversee mission-critical operations, proving high-density electrophysiology service to bridge the gap between genetics, disease modeling, and innovative drug discovery.

Key Responsibilities

The Core Director is responsible for the strategic leadership, technical integrity, and operational management of the Core. Primary duties include:

• Scientific Leadership: Provide consultative support to investigators to integrate complex electrophysiological tools into their research programs.
• Service Management: Oversee the delivery of high-throughput techniques, including advanced patch-clamp, multi-patch recording (up to 8 cells), and microelectrode arrays (MEAs).
• Technological Support: Lead the Core's Patch-seq services, combining whole-cell recording with single-cell RNA sequencing (scRNA-seq) for simultaneous physiological and transcriptomic profiling.
• Data Oversight: Supervise comprehensive data collection, quantitative analysis, and the write-up of results for publication or grant submissions.
• Training & Mentorship: Direct the training of research personnel in advanced electrophysiological techniques.
• Operational Oversight: Manage core hours (Mon-Fri, 9 am - 6 pm), personnel (including the Core technicians and staff scientists), and the internal/external billing structure.

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

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